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Farnesyl diphosphate synthase regulated endothelial proliferation and autophagy during rat pulmonary arterial hypertension induced by monocrotaline
BACKGROUND: The proliferation ability and autophagy level of pulmonary artery endothelial cells (PAECs) play an important role in promoting the development of pulmonary artery hypertension (PAH), and there is still no effective treatment for PAH. Farnesyl diphosphate synthase (FDPS) is a key enzyme...
Autores principales: | Jin, Tingting, Lu, Jiangting, Lv, Qingbo, Gong, Yingchao, Feng, Zhaojin, Ying, Hangying, Wang, Meihui, Fu, Guosheng, Jiang, Dongmei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373289/ https://www.ncbi.nlm.nih.gov/pubmed/35962329 http://dx.doi.org/10.1186/s10020-022-00511-7 |
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