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Tubular epithelial cell-derived extracellular vesicles induce macrophage glycolysis by stabilizing HIF-1α in diabetic kidney disease

BACKGROUND: Albuminuria is a hallmark of diabetic kidney disease (DKD) that promotes its progression, leading to renal fibrosis. Renal macrophage function is complex and influenced by macrophage metabolic status. However, the metabolic state of diabetic renal macrophages and the impact of albuminuri...

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Detalles Bibliográficos
Autores principales: Jia, Yijie, Chen, Jiaqi, Zheng, Zhikang, Tao, Yuan, Zhang, Shuting, Zou, Meina, Yang, Yanlin, Xue, Meng, Hu, Fang, Li, Yang, Zhang, Qian, Xue, Yaoming, Zheng, Zongji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373297/
https://www.ncbi.nlm.nih.gov/pubmed/35962319
http://dx.doi.org/10.1186/s10020-022-00525-1