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Ryanodine receptor 1-mediated Ca(2+) signaling and mitochondrial reprogramming modulate uterine serous cancer malignant phenotypes

BACKGROUND: Uterine serous cancer (USC) is the most common non-endometrioid subtype of uterine cancer, and is also the most aggressive. Most patients will die of progressively chemotherapy-resistant disease, and the development of new therapies that can target USC remains a major unmet clinical need...

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Detalles Bibliográficos
Autores principales: Zhang, Li, Au-Yeung, Chi-Lam, Huang, Chunxian, Yeung, Tsz-Lun, Ferri-Borgogno, Sammy, Lawson, Barrett C., Kwan, Suet-Ying, Yin, Zheng, Wong, Stephen T., Thomas, Vienna, Lu, Karen H., Yip, Kay-Pong, Sham, James S. K., Mok, Samuel C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373370/
https://www.ncbi.nlm.nih.gov/pubmed/35953818
http://dx.doi.org/10.1186/s13046-022-02419-w