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Effect of anesthesia induction on cerebral tissue oxygen saturation in hypertensive patients: an observational study()

OBJECTIVE: In hypertensive patients, the autoregulation curve shifts rightward, making these patients more sensitive than normotensive individuals to hypotension. Hypotension following the induction of anesthesia has been studied in normotensive patients to determine its effects on brain tissue oxyg...

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Autores principales: Taşkaldıran, Yasin, Şen, Özlem, Aşkın, Tuğba, Ünver, Süheyla
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373433/
https://www.ncbi.nlm.nih.gov/pubmed/33958185
http://dx.doi.org/10.1016/j.bjane.2021.02.010
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author Taşkaldıran, Yasin
Şen, Özlem
Aşkın, Tuğba
Ünver, Süheyla
author_facet Taşkaldıran, Yasin
Şen, Özlem
Aşkın, Tuğba
Ünver, Süheyla
author_sort Taşkaldıran, Yasin
collection PubMed
description OBJECTIVE: In hypertensive patients, the autoregulation curve shifts rightward, making these patients more sensitive than normotensive individuals to hypotension. Hypotension following the induction of anesthesia has been studied in normotensive patients to determine its effects on brain tissue oxygenation, but not enough studies have examined the effect of hypotension on brain oxygenation in hypertensive patients. The current study aimed to use near-infrared spectroscopy to evaluate brain tissue oxygen saturation after the induction of anesthesia in hypertensive patients, who may have impaired brain tissue oxygen saturation. METHODS: The study included a total of 200 patients aged > 18 years old with ASA I–III. Measurements were taken while the patient was breathing room air, after the induction of anesthesia, when the lash reflex had disappeared following the induction of anesthesia, after intubation, and in the 5th, 10th, and 15th minutes of surgery. The patients were divided into nonhypertensive and hypertensive groups. RESULTS: There was a significant difference in age between the groups (p = 0.000). No correlation was found between cerebral tissue oxygen saturation and age (r = 0.015, p = 0.596). Anesthesia induction was observed to decrease mean arterial blood pressure in both groups (p = 0.000). Given these changes, there was no significant difference in brain tissue oxygen saturation between the nonhypertensive and hypertensive groups (p > 0.05). CONCLUSION: There was no difference between hypertensive and normotensive groups in terms of the change rates in cSO(2) values. However, there was a difference between the groups in terms of cSO(2) values.
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spelling pubmed-93734332022-08-15 Effect of anesthesia induction on cerebral tissue oxygen saturation in hypertensive patients: an observational study() Taşkaldıran, Yasin Şen, Özlem Aşkın, Tuğba Ünver, Süheyla Braz J Anesthesiol Clinical Research OBJECTIVE: In hypertensive patients, the autoregulation curve shifts rightward, making these patients more sensitive than normotensive individuals to hypotension. Hypotension following the induction of anesthesia has been studied in normotensive patients to determine its effects on brain tissue oxygenation, but not enough studies have examined the effect of hypotension on brain oxygenation in hypertensive patients. The current study aimed to use near-infrared spectroscopy to evaluate brain tissue oxygen saturation after the induction of anesthesia in hypertensive patients, who may have impaired brain tissue oxygen saturation. METHODS: The study included a total of 200 patients aged > 18 years old with ASA I–III. Measurements were taken while the patient was breathing room air, after the induction of anesthesia, when the lash reflex had disappeared following the induction of anesthesia, after intubation, and in the 5th, 10th, and 15th minutes of surgery. The patients were divided into nonhypertensive and hypertensive groups. RESULTS: There was a significant difference in age between the groups (p = 0.000). No correlation was found between cerebral tissue oxygen saturation and age (r = 0.015, p = 0.596). Anesthesia induction was observed to decrease mean arterial blood pressure in both groups (p = 0.000). Given these changes, there was no significant difference in brain tissue oxygen saturation between the nonhypertensive and hypertensive groups (p > 0.05). CONCLUSION: There was no difference between hypertensive and normotensive groups in terms of the change rates in cSO(2) values. However, there was a difference between the groups in terms of cSO(2) values. Elsevier 2021-02-06 /pmc/articles/PMC9373433/ /pubmed/33958185 http://dx.doi.org/10.1016/j.bjane.2021.02.010 Text en © 2021 Sociedade Brasileira de Anestesiologia. Published by Elsevier Editora Ltda. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Clinical Research
Taşkaldıran, Yasin
Şen, Özlem
Aşkın, Tuğba
Ünver, Süheyla
Effect of anesthesia induction on cerebral tissue oxygen saturation in hypertensive patients: an observational study()
title Effect of anesthesia induction on cerebral tissue oxygen saturation in hypertensive patients: an observational study()
title_full Effect of anesthesia induction on cerebral tissue oxygen saturation in hypertensive patients: an observational study()
title_fullStr Effect of anesthesia induction on cerebral tissue oxygen saturation in hypertensive patients: an observational study()
title_full_unstemmed Effect of anesthesia induction on cerebral tissue oxygen saturation in hypertensive patients: an observational study()
title_short Effect of anesthesia induction on cerebral tissue oxygen saturation in hypertensive patients: an observational study()
title_sort effect of anesthesia induction on cerebral tissue oxygen saturation in hypertensive patients: an observational study()
topic Clinical Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373433/
https://www.ncbi.nlm.nih.gov/pubmed/33958185
http://dx.doi.org/10.1016/j.bjane.2021.02.010
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