Cargando…

Dose-related effects of dexmedetomidine on sepsis-initiated lung injury in rats

BACKGROUND: Sepsis is one of the leading causes of death in intensive care units. Dexmedetomidine is a sedative agent with anti-inflammatory properties. This study is designed to differentiate the impact of two different doses of dexmedetomidine on lung injury induced by sepsis. METHODS: Adult male...

Descripción completa

Detalles Bibliográficos
Autores principales:	Karabulut, Gülsüm, Bedirli, Nurdan, Akyürek, Nalan, Bağrıaçık, Emin Ümit
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2021
Materias:	Experimental Trials
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373509/ https://www.ncbi.nlm.nih.gov/pubmed/33845100 http://dx.doi.org/10.1016/j.bjane.2021.02.051

Ejemplares similares

Sevoflurane exerts brain-protective effects against sepsis-associated encephalopathy and memory impairment through caspase 3/9 and Bax/Bcl signaling pathway in a rat model of sepsis
por: Bedirli, Nurdan, et al.
Publicado: (2018)

Tramadol vs dexmedetomidine for emergence agitation control in pediatric patients undergoing adenotonsillectomy with sevoflurane anesthesia: prospective randomized controlled clinical study
por: Bedirli, Nurdan, et al.
Publicado: (2017)

The Effects of Dexmedetomidine on Secondary Acute Lung and Kidney Injuries in the Rat Model of Intra-Abdominal Sepsis
por: Koca, Uğur, et al.
Publicado: (2013)

Effects of rocuronium, sugammadex and rocuronium-sugammadex complex on coagulation in rats
por: Lima Cavalcanti, Ismar, et al.
Publicado: (2020)

Morphine promotes migration and lung metastasis of mouse melanoma cells
por: Vaseghi, Golnaz, et al.
Publicado: (2022)

Effects of Pre–Cardiopulmonary Bypass Administration of Dexmedetomidine on Cardiac Injuries and the Inflammatory Response in Valve Replacement Surgery With a Sevoflurane Postconditioning Protocol: A Pilot Study
por: Zhou, Hongmei, et al.
Publicado: (2019)

Acute effects of different doses of malathion on the rat liver
por: Severcan, Çınar, et al.
Publicado: (2019)

Does memantine show chemopreventive effect against mice 4T1 breast tumor model?
por: ALBAYRAK, Gülşah, et al.
Publicado: (2022)

Comparison of dexmedetomidine and three different doses of midazolam in preoperative sedation
por: Eren, Gulay, et al.
Publicado: (2011)

Initiation and tolerance of chemoprevention among women with high-risk breast lesions: the potential of low-dose tamoxifen
por: Bychkovsky, Brittany, et al.
Publicado: (2022)

Radiographic comparison of cervical spine motion using LMA Fastrach, LMA CTrach, and the Macintosh laryngoscope
por: İNAN, Gözde, et al.
Publicado: (2019)

Clinicopathological and Prognostic Significance of the EML4-ALK Translocation and IGFR1, TTF1, Napsin A Expression in Patients with Lung Adenocarcinoma
por: Bulutay, Pınar, et al.
Publicado: (2021)

Dexmedetomidine alleviates lipopolysaccharide-induced lung injury in Wistar rats
por: Yan, Xuetao, et al.
Publicado: (2017)

Heparanase inhibition leads to improvement in patients with acute gastrointestinal injuries induced by sepsis
por: Chen, Ting-Ting, et al.
Publicado: (2023)

Methylnaltrexone Treatment for Opioid-Induced Constipation in Patients with and without Cancer: Effect of Initial Dose
por: Chamberlain, Bruce H, et al.
Publicado: (2023)

Protective Effect of Dexmedetomidine on Endotoxin-Induced Acute Lung Injury in Rats
por: Meng, Peng Z., et al.
Publicado: (2018)

Dexmedetomidine preconditioning protects against lung injury in hemorrhagic shock rats
por: Zhang, Lei, et al.
Publicado: (2018)

Multiple Liver and Muscle Abscesses and Sepsis with Bacillus pantothenticus in a Leukemia Patient
por: Ümit, Elif Gülsüm, et al.
Publicado: (2014)

Ketamine Enhances Intranasal Dexmedetomidine-Induced Sedation in Children: A Randomized, Double-Blind Trial
por: Qian, Bin, et al.
Publicado: (2020)

Demonstration of ameliorating effect of papaverine in sepsis-induced acute lung injury on rat model through radiology and histology
por: Özkul, Bahattin, et al.
Publicado: (2023)

Acalabrutinib and high-frequency low-dose subcutaneous rituximab for initial therapy of chronic lymphocytic leukemia
por: Wallace, Danielle S., et al.
Publicado: (2023)

Comparison of dexmedetomidine and sufentanil as adjuvants to local anesthetic for epidural labor analgesia: a randomized controlled trial
por: Zhang, Tao, et al.
Publicado: (2019)

Comparison of dexmedetomidine or sufentanil combined with ropivacaine for epidural analgesia after thoracotomy: a randomized controlled study
por: Yan, MJ, et al.
Publicado: (2019)

Determination of the ED(95 )of intranasal sufentanil combined with intranasal dexmedetomidine for moderate sedation during endoscopic ultrasonography
por: Zou, Yi, et al.
Publicado: (2022)

Dexmedetomidine alleviated sepsis-induced myocardial ferroptosis and septic heart injury
por: Wang, Chunyan, et al.
Publicado: (2020)

Sildenafil in endotoxin-induced pulmonary hypertension: an experimental study
por: Kemper, Daniella Aparecida Godoi, et al.
Publicado: (2021)

Dexmedetomidine reduces sevoflurane EC(50) for supraglottic airway device insertion in spontaneously breathing morbidly obese patients
por: Wan, Lei, et al.
Publicado: (2019)

Spinal or Intravenous Dexmedetomidine for Spinal Anesthesia with Chloroprocaine in Ambulatory Knee Arthroscopies: A Double-Blind Randomized Trial
por: Breebaart, Margaretha B, et al.
Publicado: (2021)

Clinically suspected anaphylaxis induced by sugammadex in a patient with Weaver syndrome undergoing restrictive mammoplasty surgery: A case report with the literature review
por: Bedirli, Nurdan, et al.
Publicado: (2018)

Dexmedetomidine may upregulate the expression of caveolin-1 in lung tissues of rats with sepsis and improve the short-term outcome
por: Zhang, Yun, et al.
Publicado: (2017)

Dexmedetomidine and propofol sedation requirements in an autistic rat model
por: Elmorsy, Soha A., et al.
Publicado: (2019)

Effects of intrathecal dexmedetomidine on shivering after spinal anesthesia for cesarean section: a double-blind randomized clinical trial
por: Nasseri, Karim, et al.
Publicado: (2017)

2311: Coronary artery calcification on nongated CT scan predicts mortality and acute myocardial infarction after sepsis
por: Arun Gupta, Vedant, et al.
Publicado: (2018)

Effect of carbamazepine on dolutegravir pharmacokinetics and dosing recommendation
por: Song, Ivy, et al.
Publicado: (2016)

Dexmedetomidine for the prevention of emergence delirium and postoperative behavioral changes in pediatric patients with sevoflurane anesthesia: a double-blind, randomized trial
por: Shi, Mengzhu, et al.
Publicado: (2019)

Impact of intravenous dexmedetomidine on postoperative bowel movement recovery after laparoscopic nephrectomy: A consort-prospective, randomized, controlled trial
por: Huang, Shan-Shan, et al.
Publicado: (2021)

Effect of dexmedetomidine on lung ischemia-reperfusion injury
por: JIANG, LILI, et al.
Publicado: (2014)

Dexmedetomidine May Produce Extra Protective Effects on Sepsis-induced Diaphragm Injury
por: Wu, Jin, et al.
Publicado: (2015)

Dexmedetomidine attenuates inflammation and organ injury partially by upregulating Nur77 in sepsis
por: Zhang, Qian, et al.
Publicado: (2023)

The determination of the protective role of sildenafil administration in rats with sepsis-induced liver injury
por: Cerrah, Serkan, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_o7ot6dq1822motmkqff1haqioc