Identification of LARS as an essential gene for osteosarcoma proliferation through large-Scale CRISPR-Cas9 screening database and experimental verification

BACKGROUND: Osteosarcoma is one of the most malignant tumors, and it occurs mostly in children and adolescents. Currently, surgery and chemotherapy are the main treatments. The recurrence rate is high and the prognosis is often poor. Finding an effective target gene therapy for osteosarcoma may effe...

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Detalles Bibliográficos
Autores principales: Chen, Wenhao, Lin, Yuxiang, Jiang, Meichen, Wang, Qingshui, Shu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373537/
https://www.ncbi.nlm.nih.gov/pubmed/35962451
http://dx.doi.org/10.1186/s12967-022-03571-9

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