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Autophagy activation attenuates the neurotoxicity of local anesthetics by decreasing caspase-3 activity in rats

BACKGROUND AND OBJECTIVES: The mechanisms by which local anesthetics cause neurotoxicity are very complicated. Apoptosis and autophagy are highly coordinated mechanisms that maintain cellular homeostasis against stress. Studies have shown that autophagy activation serves as a protective mechanism in...

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Detalles Bibliográficos
Autores principales: Xue, Xing, Lv, Ying, Leng, Yufang, Zhang, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373661/
https://www.ncbi.nlm.nih.gov/pubmed/33280811
http://dx.doi.org/10.1016/j.bjane.2020.11.001