CRISPR/Cas9-based genome-wide screening for deubiquitinase subfamily identifies USP1 regulating MAST1-driven cisplatin-resistance in cancer cells

Background: Cisplatin is one of the frontline anticancer agents. However, development of cisplatin-resistance limits the therapeutic efficacy of cisplatin-based treatment. The expression of microtubule-associated serine/threonine kinase 1 (MAST1) is a primary factor driving cisplatin-resistance in c...

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Detalles Bibliográficos
Autores principales: Tyagi, Apoorvi, Kaushal, Kamini, Chandrasekaran, Arun Pandian, Sarodaya, Neha, Das, Soumyadip, Park, Chang-Hwan, Hong, Seok-Ho, Kim, Kye-Seong, Ramakrishna, Suresh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2022
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373805/
https://www.ncbi.nlm.nih.gov/pubmed/35966591
http://dx.doi.org/10.7150/thno.72826

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