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LRRC8A critically regulates myofibroblast phenotypes and fibrotic remodeling following myocardial infarction
Rationale: The transformation of fibroblasts into activated myofibroblasts is a critical step that results in cardiac fibrosis upon myocardial infarction (MI). Leucine-rich repeat-containing protein-8A (LRRC8A) is a multi-functional protein involved in cell survival, growth, and proliferation, where...
Autores principales: | Chen, Xiyao, Zhang, Fuyang, Hu, Guangyu, Li, Xing, Wang, Lin, Li, Congye, Huo, Cong, Xu, Rong, Hou, Liming, Wang, Ning, Wang, Xiaoming |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Ivyspring International Publisher
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373806/ https://www.ncbi.nlm.nih.gov/pubmed/35966575 http://dx.doi.org/10.7150/thno.75200 |
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