Cargando…

Lgr5(+) cells are required and dynamically participate in olfactory epithelium regeneration: a revisiting shows Lgr5 expression in multiple cell lineages

Olfactory sensory neurons (OSNs) located in the olfactory epithelium (OE) detect thousands of volatile environmental odors to form the sense of smell. OSNs are generated from basal cells, which show the characteristics of progenitor/stem cells. In the mammalian OE, persistent neurogenesis occurs dur...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ren, Wenwen, Ma, Zhenjie, Wang, Li, Feng, Xiaoyu, Yu, Hongmeng, Yu, Yiqun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373817/ https://www.ncbi.nlm.nih.gov/pubmed/35966594 http://dx.doi.org/10.7150/thno.60636

Ejemplares similares

Age-Dependent Activation and Neuronal Differentiation of Lgr5+ Basal Cells in Injured Olfactory Epithelium via Notch Signaling Pathway
por: Li, Xuewen, et al.
Publicado: (2020)

LGR4 and LGR5 Regulate Hair Cell Differentiation in the Sensory Epithelium of the Developing Mouse Cochlea
por: Żak, Magdalena, et al.
Publicado: (2016)

LGR5 and LGR6 in stem cell biology and ovarian cancer
por: Schindler, Adam J., et al.
Publicado: (2017)

Quantifying Lgr5-positive stem cell behaviour in the pyloric epithelium
por: Leushacke, Marc, et al.
Publicado: (2016)

Characterization of the Transcriptomes of Lgr5+ Hair Cell Progenitors and Lgr5- Supporting Cells in the Mouse Cochlea
por: Cheng, Cheng, et al.
Publicado: (2017)

LGR4 and LGR5 Function Redundantly During Human Endoderm Differentiation
por: Tsai, Yu-Hwai, et al.
Publicado: (2016)

Monolayer culture of intestinal epithelium sustains Lgr5(+) intestinal stem cells
por: Liu, Yuan, et al.
Publicado: (2018)

Anatomically and Functionally Distinct Lung Mesenchymal Populations Marked by Lgr5 and Lgr6
por: Lee, Joo-Hyeon, et al.
Publicado: (2017)

Lgr5 in cancer biology: functional identification of Lgr5 in cancer progression and potential opportunities for novel therapy
por: Xu, Liangliang, et al.
Publicado: (2019)

Generating tissue-engineered intestinal epithelium from cultured Lgr5 stem cells in vivo
por: Baimakhanov, Zhassulan, et al.
Publicado: (2016)

MEX3A regulates Lgr5 (+) stem cell maintenance in the developing intestinal epithelium
por: Pereira, Bruno, et al.
Publicado: (2020)

Lgr5 Identifies Progenitor Cells Capable of Taste Bud Regeneration after Injury
por: Takeda, Norifumi, et al.
Publicado: (2013)

LGR4 and LGR5 form distinct homodimers that only LGR4 complexes with RNF43/ZNRF3 to provide high affinity binding of R-spondin ligands
por: Toh, Yukimatsu, et al.
Publicado: (2023)

Castration-Resistant Lgr5(+) Cells Are Long-Lived Stem Cells Required for Prostatic Regeneration
por: Wang, Bu-er, et al.
Publicado: (2015)

Characterization of Lgr6+ Cells as an Enriched Population of Hair Cell Progenitors Compared to Lgr5+ Cells for Hair Cell Generation in the Neonatal Mouse Cochlea
por: Zhang, Yanping, et al.
Publicado: (2018)

Cytoplasmic expression of LGR5 in pancreatic adenocarcinoma
por: Mizuno, Nobumasa, et al.
Publicado: (2013)

Transcriptome profiling of LGR5 positive colorectal cancer cells
por: Hirsch, Daniela, et al.
Publicado: (2014)

Stem Cell Markers in Neuroblastoma—An Emerging Role for LGR5
por: Forgham, Helen, et al.
Publicado: (2015)

Characterization of LGR5 stem cells in colorectal adenomas and carcinomas
por: Baker, Ann-Marie, et al.
Publicado: (2015)

Heterogeneity of the Level of Activity of Lgr5+ Intestinal Stem Cells
por: Moossavi, Shirin
Publicado: (2014)

Lgr5(+) intestinal stem cell sorting and organoid culture
por: Liu, Ruixue, et al.
Publicado: (2019)

Role of LGR5-positive mesenchymal cells in craniofacial development
por: Olbertová, Kristýna, et al.
Publicado: (2022)

R-Spondin Potentiates Wnt/β-Catenin Signaling through Orphan Receptors LGR4 and LGR5
por: Ruffner, Heinz, et al.
Publicado: (2012)

Transcriptome Analysis Did Not Show Endogenous Stem Cell Characteristics in Murine Lgr5(+) Retinal Cells
por: Trepp, Carolyn, et al.
Publicado: (2019)

Emerging role for leucine-rich repeat-containing G-protein-coupled receptors LGR5 and LGR4 in cancer stem cells
por: Nakata, Susumu, et al.
Publicado: (2014)

Lgr5(+) intestinal stem cells reside in an unlicensed G(1) phase
por: Carroll, Thomas D., et al.
Publicado: (2018)

The Spatial Distribution of LGR5(+) Cells Correlates With Gastric Cancer Progression
por: Simon, Eva, et al.
Publicado: (2012)

Knockdown of LGR5 suppresses the proliferation of glioma cells in vitro and in vivo
por: WANG, DONGLIANG, et al.
Publicado: (2014)

Effects of dose rates on radiation-induced replenishment of intestinal stem cells determined by Lgr5 lineage tracing
por: Otsuka, Kensuke, et al.
Publicado: (2015)

Lgr5 and Col22a1 Mark Progenitor Cells in the Lineage toward Juvenile Articular Chondrocytes
por: Feng, Chen, et al.
Publicado: (2019)

Lgr5+ Cells Regenerate Hair Cells via Proliferation and Direct Transdifferentiation in Damaged Neonatal Mouse Utricle
por: Wang, Tian, et al.
Publicado: (2015)

Canine Epithelial Skin Tumours: Expression of the Stem Cell Markers Lgr5, Lgr6 and Sox9 in Light of New Cancer Stem Cell Theories
por: Bongiovanni, Laura, et al.
Publicado: (2020)

Colon Crypts of Subjects With Familial Adenomatous Polyposis Show an Increased Number of LGR5+ Ectopic Stem Cells
por: Jennelle, Lucas T., et al.
Publicado: (2021)

Clinical Significance of Stem Cell Biomarkers EpCAM, LGR5 and LGR4 mRNA Levels in Lymph Nodes of Colon Cancer Patients
por: AbdelMageed, Manar, et al.
Publicado: (2021)

Prognostic Value of LGR5 in Colorectal Cancer: A Meta-Analysis
por: Chen, Qing, et al.
Publicado: (2014)

Pten loss in Lgr5(+) hair follicle stem cells promotes SCC development
por: Chen, Haiyan, et al.
Publicado: (2019)

LGR5 is associated with tumor aggressiveness in papillary thyroid cancer
por: Michelotti, Gregory, et al.
Publicado: (2015)

Differential epithelial and stromal LGR5 expression in ovarian carcinogenesis
por: Kim, Hyesung, et al.
Publicado: (2022)

Lgr5 Marks Post-Mitotic, Lineage Restricted Cerebellar Granule Neurons during Postnatal Development
por: Miller, Tyler E., et al.
Publicado: (2014)

LGR5 is required for the maintenance of spheroid-derived colon cancer stem cells
por: CHEN, XIANG, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_lqppc9c0iq2qspv2m6ohj3hsli