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A CRISPR-Cas12a integrated SERS nanoplatform with chimeric DNA/RNA hairpin guide for ultrasensitive nucleic acid detection

Background: CRISPR-Cas12a has been integrated with nanomaterial-based optical techniques, such as surface-enhanced Raman scattering (SERS), to formulate a powerful amplification-free nucleic acid detection system. However, nanomaterials impose steric hindrance to limit the accessibility of CRISPR-Ca...

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Detalles Bibliográficos
Autores principales:	Yin, Bohan, Zhang, Qin, Xia, Xinyue, Li, Chuanqi, Ho, Willis Kwun Hei, Yan, Jiaxiang, Huang, Yingying, Wu, Honglian, Wang, Pui, Yi, Changqing, Hao, Jianhua, Wang, Jianfang, Chen, Honglin, Wong, Siu Hong Dexter, Yang, Mo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Ivyspring International Publisher 2022
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9373821/ https://www.ncbi.nlm.nih.gov/pubmed/35966585 http://dx.doi.org/10.7150/thno.75816

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