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Characterization of Cathepsin B in Mediating Silica Nanoparticle-Induced Macrophage Pyroptosis via an NLRP3-Dependent Manner

INTRODUCTION: Silica nanoparticles (SiNPs) are one of the most widely used inorganic nanomaterials, and exposure to SiNP has been demonstrated to induce pulmonary inflammation, primarily promoted by the NLRP3-mediated macrophage pyroptosis. However, mechanisms underlying the activation of NLRP3 sign...

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Detalles Bibliográficos
Autores principales:	Ma, Lan, Han, Zhengpu, Yin, Haoyu, Tian, Jiaqi, Zhang, Jing, Li, Ning, Ding, Chunjie, Zhang, Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2022
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374095/ https://www.ncbi.nlm.nih.gov/pubmed/35966002 http://dx.doi.org/10.2147/JIR.S371536

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