Antibiotic resistance pattern of Helicobacter pylori strains isolated from patients in Isfahan, Iran

BACKGROUND: The objective of this study was to evaluate the antibiotic resistance pattern of Helicobacter pylori strains isolated from patients in Isfahan province. MATERIALS AND METHODS: Gastric antrum biopsy specimens of patients undergoing endoscopy were cultured. The samples with the growth of H...

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Detalles Bibliográficos
Autores principales: Sadeghi, Hajarsadat, Narimani, Tahmineh, Tabesh, Elham, Shafiee, Fatemeh, Soltani, Rasool
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2022
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374139/
https://www.ncbi.nlm.nih.gov/pubmed/35968205
http://dx.doi.org/10.4103/jrms.jrms_829_21
Descripción
Sumario:BACKGROUND: The objective of this study was to evaluate the antibiotic resistance pattern of Helicobacter pylori strains isolated from patients in Isfahan province. MATERIALS AND METHODS: Gastric antrum biopsy specimens of patients undergoing endoscopy were cultured. The samples with the growth of H. pylori underwent antibiotic susceptibility test by disk diffusion method. REAULTS: Of 96 samples, 50 samples (53%) were positive for H. pylori. The rates of antibiotic resistance were as follows: amoxicillin, 6%; azithromycin, 20%; furazolidone, 22%; levofloxacin, 16%; metronidazole, 20%; rifampin, 12%; and tetracycline, 22%. CONCLUSION: H. pylori strains in our area have high rates of resistance to azithromycin, levofloxacin, metronidazole, tetracycline, and furazolidone.

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