Preparation and Evaluation of Low-Dose Calcitriol Dry Powder Inhalation as Host-Directed Adjunct Therapy for Tuberculosis

BACKGROUND: It is unclear whether Vitamin D is efficacious as a host-directed therapy (HDT) for patients of tuberculosis (TB). We investigated pulmonary delivery of the active metabolite of Vitamin D(3), i.e., 1, 25-dihydroxy vitamin D(3) (calcitriol) in a mouse model of infection with Mycobacterium...

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Detalles Bibliográficos
Autores principales: Reddy, D. V. Siva, Shafi, Hasham, Bharti, Reena, Roy, Trisha, Verma, Sonia, Raman, Sunil Kumar, Verma, Khushboo, Azmi, Lubna, Ray, Lipika, Singh, Jyotsna, Singh, Amit Kumar, Mugale, Madhav N., Misra, Amit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2022
Materias:
Original Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374297/
https://www.ncbi.nlm.nih.gov/pubmed/35962268
http://dx.doi.org/10.1007/s11095-022-03360-5

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