Upregulated PD-1 signaling antagonizes glomerular health in aged kidneys and disease

With an aging population, kidney health becomes an important medical and socioeconomic factor. Kidney aging mechanisms are not well understood. We previously showed that podocytes isolated from aged mice exhibit increased expression of programmed cell death protein 1 (PD-1) surface receptor and its...

Descripción completa

Detalles Bibliográficos
Autores principales: Pippin, Jeffrey W., Kaverina, Natalya, Wang, Yuliang, Eng, Diana G., Zeng, Yuting, Tran, Uyen, Loretz, Carol J., Chang, Anthony, Akilesh, Shreeram, Poudel, Chetan, Perry, Hannah S., O’Connor, Christopher, Vaughan, Joshua C., Bitzer, Markus, Wessely, Oliver, Shankland, Stuart J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Clinical Investigation 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374384/
https://www.ncbi.nlm.nih.gov/pubmed/35968783
http://dx.doi.org/10.1172/JCI156250

Ejemplares similares

Ejemplares similares