Generation of functional hepatocytes by forward programming with nuclear receptors

Production of large quantities of hepatocytes remains a major challenge for a number of clinical applications in the biomedical field. Directed differentiation of human pluripotent stem cells (hPSCs) into hepatocyte-like cells (HLCs) provides an advantageous solution and a number of protocols have b...

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Detalles Bibliográficos
Autores principales: Tomaz, Rute A, Zacharis, Ekaterini D, Bachinger, Fabian, Wurmser, Annabelle, Yamamoto, Daniel, Petrus-Reurer, Sandra, Morell, Carola M, Dziedzicka, Dominika, Wesley, Brandon T, Geti, Imbisaat, Segeritz, Charis-Patricia, de Brito, Miguel C, Chhatriwala, Mariya, Ortmann, Daniel, Saeb-Parsy, Kourosh, Vallier, Ludovic
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2022
Materias:
Stem Cells and Regenerative Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374437/
https://www.ncbi.nlm.nih.gov/pubmed/35959725
http://dx.doi.org/10.7554/eLife.71591

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