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METTL3 antagonizes 5-FU chemotherapy and confers drug resistance in colorectal carcinoma
Colorectal cancer (CRC) is one of top five leading causes of cancer-associated mortalities worldwide. 5-Fluorouracil (5-FU) is the first-line chemotherapeutic drug in the treatment of CRC; however, its antineoplastic efficiency is limited due to acquired drug resistance. The regulatory mechanism und...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374465/ https://www.ncbi.nlm.nih.gov/pubmed/35856434 http://dx.doi.org/10.3892/ijo.2022.5396 |