METTL3 antagonizes 5-FU chemotherapy and confers drug resistance in colorectal carcinoma

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Colorectal cancer (CRC) is one of top five leading causes of cancer-associated mortalities worldwide. 5-Fluorouracil (5-FU) is the first-line chemotherapeutic drug in the treatment of CRC; however, its antineoplastic efficiency is limited due to acquired drug resistance. The regulatory mechanism und...

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Detalles Bibliográficos
Autores principales: Li, Min, Xia, Mingyue, Zhang, Ziyu, Tan, Yanyin, Li, Enjie, Guo, Zhigang, Fang, Mingzhi, Zhu, Yong, Hu, Zhigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2022
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374465/
https://www.ncbi.nlm.nih.gov/pubmed/35856434
http://dx.doi.org/10.3892/ijo.2022.5396
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