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Bioinformatic analysis of PD-1 checkpoint blockade response in influenza infection

BACKGROUND: The programmed cell death 1 (PD-1)/PD-1 ligand 1 (PD-L1) signaling pathway is significantly upregulated in influenza virus infection, which impairs the antiviral response. Blocking this signaling pathway may reduce the damage, lower the virus titer in lung tissue, and alleviate the sympt...

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Detalles Bibliográficos
Autores principales: Ou, Huilin, Chen, Keda, Chen, Linfang, Wu, Hongcheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374577/
https://www.ncbi.nlm.nih.gov/pubmed/35962325
http://dx.doi.org/10.1186/s12863-022-01081-7