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Bioinformatic analysis of PD-1 checkpoint blockade response in influenza infection
BACKGROUND: The programmed cell death 1 (PD-1)/PD-1 ligand 1 (PD-L1) signaling pathway is significantly upregulated in influenza virus infection, which impairs the antiviral response. Blocking this signaling pathway may reduce the damage, lower the virus titer in lung tissue, and alleviate the sympt...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374577/ https://www.ncbi.nlm.nih.gov/pubmed/35962325 http://dx.doi.org/10.1186/s12863-022-01081-7 |