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CircME1 promotes aerobic glycolysis and sunitinib resistance of clear cell renal cell carcinoma through cis-regulation of ME1

Circular RNAs (circRNAs) play critical roles in clear cell renal cell carcinoma (ccRCC). However, their involvement in sunitinib resistance remains largely unknown. Herein, we identified a novel circRNA, named circME1, which contributes to sunitinib resistance development in ccRCC. CircME1 also prom...

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Detalles Bibliográficos
Autores principales: Zhang, Ming-xiao, Wang, Jia-li, Mo, Cheng-qiang, Mao, Xiao-peng, Feng, Zi-hao, Li, Jia-ying, Lin, Hai-shan, Song, Hong-de, Xu, Quan-hui, Wang, Ying-han, Lu, Jun, Wei, Jin-huan, Han, Hui, Chen, Wei, Mao, Hai-ping, Luo, Jun-hang, Chen, Zhen-hua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374592/
https://www.ncbi.nlm.nih.gov/pubmed/35798876
http://dx.doi.org/10.1038/s41388-022-02386-8