PD1/PD-L1 immune checkpoint as a potential target for preventing brain tumor progression

Programmed death-1 (PD-1) is a cell surface receptor that functions as a T cell checkpoint and plays a central role in regulating T cell collapse. The binding of PD-1 to its ligand programmed death-ligand 1 (PD-L1) activates downstream signaling pathways and inhibits T cell activation in the perspec...

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Detalles Bibliográficos
Autores principales: Filippone, A., Lanza, M., Mannino, D., Raciti, G., Colarossi, C., Sciacca, D., Cuzzocrea, S., Paterniti, I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2022
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374620/
https://www.ncbi.nlm.nih.gov/pubmed/35092481
http://dx.doi.org/10.1007/s00262-021-03130-z

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