Identification of key interactions of benzimidazole resistance-associated amino acid mutations in Ascaris β-tubulins by molecular docking simulations

Ascaris species are soil-transmitted helminths that infect humans and livestock mainly in low and middle-income countries. Benzimidazole (BZ) class drugs have predominated for many years in the treatment of Ascaris infections, but persistent use of BZs has already led to widespread resistance in oth...

Descripción completa

Detalles Bibliográficos
Autores principales: Jones, Ben P., van Vliet, Arnoud H. M., LaCourse, E. James, Betson, Martha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374697/
https://www.ncbi.nlm.nih.gov/pubmed/35961997
http://dx.doi.org/10.1038/s41598-022-16765-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374697/
https://www.ncbi.nlm.nih.gov/pubmed/35961997
http://dx.doi.org/10.1038/s41598-022-16765-4

Ejemplares similares