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Oral sorafenib-loaded microemulsion for breast cancer: evidences from the in-vitro evaluations and pharmacokinetic studies
Sorafenib tosylate (SFB) is a multikinase inhibitor that inhibits tumour growth and proliferation for the management of breast cancer but is also associated with issues like toxicity and drug resistance. Also, being a biopharmaceutical class II (BCS II) drug, its oral bioavailability is the other ch...
Autores principales: | Chaurawal, Nishtha, Misra, Charu, Abul Barkat, Harshita, Jatyan, Reena, Chitkara, Deepak, Barkat, Md. Abul, Sharma, Teenu, Singh, Bhupinder, Raza, Kaisar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374710/ https://www.ncbi.nlm.nih.gov/pubmed/35962160 http://dx.doi.org/10.1038/s41598-022-17333-6 |
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