In vivo transomic analyses of glucose-responsive metabolism in skeletal muscle reveal core differences between the healthy and obese states

Metabolic regulation in skeletal muscle is essential for blood glucose homeostasis. Obesity causes insulin resistance in skeletal muscle, leading to hyperglycemia and type 2 diabetes. In this study, we performed multiomic analysis of the skeletal muscle of wild-type (WT) and leptin-deficient obese (...

Descripción completa

Detalles Bibliográficos
Autores principales: Kokaji, Toshiya, Eto, Miki, Hatano, Atsushi, Yugi, Katsuyuki, Morita, Keigo, Ohno, Satoshi, Fujii, Masashi, Hironaka, Ken-ichi, Ito, Yuki, Egami, Riku, Uematsu, Saori, Terakawa, Akira, Pan, Yifei, Maehara, Hideki, Li, Dongzi, Bai, Yunfan, Tsuchiya, Takaho, Ozaki, Haruka, Inoue, Hiroshi, Kubota, Hiroyuki, Suzuki, Yutaka, Hirayama, Akiyoshi, Soga, Tomoyoshi, Kuroda, Shinya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374747/
https://www.ncbi.nlm.nih.gov/pubmed/35962137
http://dx.doi.org/10.1038/s41598-022-17964-9

Ejemplares similares

Ejemplares similares