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A miR-34a-guided, tRNA(i)(Met)-derived, piR_019752-like fragment (tRiMetF31) suppresses migration and angiogenesis of breast cancer cells via targeting PFKFB3

Although we recently demonstrated that miR-34a directly targets tRNA(i)(Met) precursors via Argonaute 2 (AGO2)-mediated cleavage, consequently attenuating the proliferation of breast cancer cells, whether tRNA(i)(Met) fragments derived from this cleavage influence breast tumor angiogenesis remains u...

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Detalles Bibliográficos
Autores principales: Wang, Bo, Li, Dongping, Ilnytskyy, Yaroslav, Kovalchuk, Igor, Kovalchuk, Olga
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9374763/
https://www.ncbi.nlm.nih.gov/pubmed/35961977
http://dx.doi.org/10.1038/s41420-022-01054-w

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