Cargando…

The effects of the covid-19 pandemic on puberty: a cross-sectional, multicenter study from Turkey

BACKGROUNDS: During the Coronavirus-19 disease (Covid-19) pandemic it was observed that the number of girls presenting with early puberty had increased. The aim of this study was to carry out a retrospective evaluation of the characteristics of girls who had been referred for evaluation of precociou...

Descripción completa

Detalles Bibliográficos
Autores principales: Yesiltepe Mutlu, Gul, Eviz, Elif, Haliloglu, Belma, Kirmizibekmez, Heves, Dursun, Fatma, Ozalkak, Servan, Cayir, Atilla, Sacli, Beste Yuksel, Ozbek, Mehmet Nuri, Demirbilek, Huseyin, Hatun, Sukru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375063/
https://www.ncbi.nlm.nih.gov/pubmed/35964090
http://dx.doi.org/10.1186/s13052-022-01337-z
_version_ 1784767878897074176
author Yesiltepe Mutlu, Gul
Eviz, Elif
Haliloglu, Belma
Kirmizibekmez, Heves
Dursun, Fatma
Ozalkak, Servan
Cayir, Atilla
Sacli, Beste Yuksel
Ozbek, Mehmet Nuri
Demirbilek, Huseyin
Hatun, Sukru
author_facet Yesiltepe Mutlu, Gul
Eviz, Elif
Haliloglu, Belma
Kirmizibekmez, Heves
Dursun, Fatma
Ozalkak, Servan
Cayir, Atilla
Sacli, Beste Yuksel
Ozbek, Mehmet Nuri
Demirbilek, Huseyin
Hatun, Sukru
author_sort Yesiltepe Mutlu, Gul
collection PubMed
description BACKGROUNDS: During the Coronavirus-19 disease (Covid-19) pandemic it was observed that the number of girls presenting with early puberty had increased. The aim of this study was to carry out a retrospective evaluation of the characteristics of girls who had been referred for evaluation of precocious puberty in five different pediatric endocrinology units, before and during the pandemic. METHODS: The study participants comprised 359 girls who were assigned into 2 groups a pre-pandemic group (n:214) and a pandemic group (n:145). Those participants (n:99) who had medical records in the follow-up period were classified into 3 subgroups according to the time of presentation and follow-up visits (group-1: first admission and follow-up visit before the pandemic, group-2: first admission before the pandemic, the follow-up visit during the pandemic, group-3: first admission and follow-up visit during the pandemic). RESULTS: The age at presentation and age at pubertal onset were both significantly lower in the pandemic group than those in the pre-pandemic group(8.1 vs 8.6, p: < 0.001,7.7 vs 7.9,p:0.013, respectively). There was no significant difference between the body mass index standard deviation scores (BMI-SDS) values of the groups (0.57 vs 0.51, p:0.430). The initiation rate of pubertal suppression therapy at the time of presentation was significantly higher in the pandemic group compared to that of the pre-pandemic group (7.7%vs 27.5%), and in groups-2 & 3 compared to group-1, during follow-up (20%&44%vs 8%). CONCLUSION: Our research showed that the onset of puberty occurred earlier in the pandemic period compared to the previous year, and the need for pubertal suppression therapy increased during the pandemic.
format Online
Article
Text
id pubmed-9375063
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-93750632022-08-14 The effects of the covid-19 pandemic on puberty: a cross-sectional, multicenter study from Turkey Yesiltepe Mutlu, Gul Eviz, Elif Haliloglu, Belma Kirmizibekmez, Heves Dursun, Fatma Ozalkak, Servan Cayir, Atilla Sacli, Beste Yuksel Ozbek, Mehmet Nuri Demirbilek, Huseyin Hatun, Sukru Ital J Pediatr Research BACKGROUNDS: During the Coronavirus-19 disease (Covid-19) pandemic it was observed that the number of girls presenting with early puberty had increased. The aim of this study was to carry out a retrospective evaluation of the characteristics of girls who had been referred for evaluation of precocious puberty in five different pediatric endocrinology units, before and during the pandemic. METHODS: The study participants comprised 359 girls who were assigned into 2 groups a pre-pandemic group (n:214) and a pandemic group (n:145). Those participants (n:99) who had medical records in the follow-up period were classified into 3 subgroups according to the time of presentation and follow-up visits (group-1: first admission and follow-up visit before the pandemic, group-2: first admission before the pandemic, the follow-up visit during the pandemic, group-3: first admission and follow-up visit during the pandemic). RESULTS: The age at presentation and age at pubertal onset were both significantly lower in the pandemic group than those in the pre-pandemic group(8.1 vs 8.6, p: < 0.001,7.7 vs 7.9,p:0.013, respectively). There was no significant difference between the body mass index standard deviation scores (BMI-SDS) values of the groups (0.57 vs 0.51, p:0.430). The initiation rate of pubertal suppression therapy at the time of presentation was significantly higher in the pandemic group compared to that of the pre-pandemic group (7.7%vs 27.5%), and in groups-2 & 3 compared to group-1, during follow-up (20%&44%vs 8%). CONCLUSION: Our research showed that the onset of puberty occurred earlier in the pandemic period compared to the previous year, and the need for pubertal suppression therapy increased during the pandemic. BioMed Central 2022-08-13 /pmc/articles/PMC9375063/ /pubmed/35964090 http://dx.doi.org/10.1186/s13052-022-01337-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research
Yesiltepe Mutlu, Gul
Eviz, Elif
Haliloglu, Belma
Kirmizibekmez, Heves
Dursun, Fatma
Ozalkak, Servan
Cayir, Atilla
Sacli, Beste Yuksel
Ozbek, Mehmet Nuri
Demirbilek, Huseyin
Hatun, Sukru
The effects of the covid-19 pandemic on puberty: a cross-sectional, multicenter study from Turkey
title The effects of the covid-19 pandemic on puberty: a cross-sectional, multicenter study from Turkey
title_full The effects of the covid-19 pandemic on puberty: a cross-sectional, multicenter study from Turkey
title_fullStr The effects of the covid-19 pandemic on puberty: a cross-sectional, multicenter study from Turkey
title_full_unstemmed The effects of the covid-19 pandemic on puberty: a cross-sectional, multicenter study from Turkey
title_short The effects of the covid-19 pandemic on puberty: a cross-sectional, multicenter study from Turkey
title_sort effects of the covid-19 pandemic on puberty: a cross-sectional, multicenter study from turkey
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375063/
https://www.ncbi.nlm.nih.gov/pubmed/35964090
http://dx.doi.org/10.1186/s13052-022-01337-z
work_keys_str_mv AT yesiltepemutlugul theeffectsofthecovid19pandemiconpubertyacrosssectionalmulticenterstudyfromturkey
AT evizelif theeffectsofthecovid19pandemiconpubertyacrosssectionalmulticenterstudyfromturkey
AT haliloglubelma theeffectsofthecovid19pandemiconpubertyacrosssectionalmulticenterstudyfromturkey
AT kirmizibekmezheves theeffectsofthecovid19pandemiconpubertyacrosssectionalmulticenterstudyfromturkey
AT dursunfatma theeffectsofthecovid19pandemiconpubertyacrosssectionalmulticenterstudyfromturkey
AT ozalkakservan theeffectsofthecovid19pandemiconpubertyacrosssectionalmulticenterstudyfromturkey
AT cayiratilla theeffectsofthecovid19pandemiconpubertyacrosssectionalmulticenterstudyfromturkey
AT saclibesteyuksel theeffectsofthecovid19pandemiconpubertyacrosssectionalmulticenterstudyfromturkey
AT ozbekmehmetnuri theeffectsofthecovid19pandemiconpubertyacrosssectionalmulticenterstudyfromturkey
AT demirbilekhuseyin theeffectsofthecovid19pandemiconpubertyacrosssectionalmulticenterstudyfromturkey
AT hatunsukru theeffectsofthecovid19pandemiconpubertyacrosssectionalmulticenterstudyfromturkey
AT yesiltepemutlugul effectsofthecovid19pandemiconpubertyacrosssectionalmulticenterstudyfromturkey
AT evizelif effectsofthecovid19pandemiconpubertyacrosssectionalmulticenterstudyfromturkey
AT haliloglubelma effectsofthecovid19pandemiconpubertyacrosssectionalmulticenterstudyfromturkey
AT kirmizibekmezheves effectsofthecovid19pandemiconpubertyacrosssectionalmulticenterstudyfromturkey
AT dursunfatma effectsofthecovid19pandemiconpubertyacrosssectionalmulticenterstudyfromturkey
AT ozalkakservan effectsofthecovid19pandemiconpubertyacrosssectionalmulticenterstudyfromturkey
AT cayiratilla effectsofthecovid19pandemiconpubertyacrosssectionalmulticenterstudyfromturkey
AT saclibesteyuksel effectsofthecovid19pandemiconpubertyacrosssectionalmulticenterstudyfromturkey
AT ozbekmehmetnuri effectsofthecovid19pandemiconpubertyacrosssectionalmulticenterstudyfromturkey
AT demirbilekhuseyin effectsofthecovid19pandemiconpubertyacrosssectionalmulticenterstudyfromturkey
AT hatunsukru effectsofthecovid19pandemiconpubertyacrosssectionalmulticenterstudyfromturkey