A dysregulated sebum–microbial metabolite–IL-33 axis initiates skin inflammation in atopic dermatitis

Microbial dysbiosis in the skin has been implicated in the pathogenesis of atopic dermatitis (AD); however, whether and how changes in the skin microbiome initiate skin inflammation, or vice versa, remains poorly understood. Here, we report that the levels of sebum and its microbial metabolite, prop...

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Detalles Bibliográficos
Autores principales: Qiu, Zhuoqiong, Zhu, Zhenlai, Liu, Xiaochun, Chen, Baichao, Yin, Huibin, Gu, Chaoying, Fang, Xiaokai, Zhu, Ronghui, Yu, Tianze, Mi, Wenli, Zhou, Hong, Zhou, Yufeng, Yao, Xu, Li, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375142/
https://www.ncbi.nlm.nih.gov/pubmed/35977109
http://dx.doi.org/10.1084/jem.20212397

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