Helminths revive to survive

Helminth parasites are well known to have co-evolved a diverse arsenal of immunomodulatory factors to aid their persistence following infection. In this issue, Karo-Atar et al. (2022. J. Exp. Med. https://doi.org/10.1084/jem.20212311) demonstrate that products released by the gut-dwelling helminth H...

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Detalles Bibliográficos
Autores principales: Grainger, John R., Daw, Rufus H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2022
Materias:
Insights
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375159/
https://www.ncbi.nlm.nih.gov/pubmed/37559179
http://dx.doi.org/10.1084/jem.20221183
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author Grainger, John R.
Daw, Rufus H.
author_facet Grainger, John R.
Daw, Rufus H.
author_sort Grainger, John R.
collection PubMed
description Helminth parasites are well known to have co-evolved a diverse arsenal of immunomodulatory factors to aid their persistence following infection. In this issue, Karo-Atar et al. (2022. J. Exp. Med. https://doi.org/10.1084/jem.20212311) demonstrate that products released by the gut-dwelling helminth Heligmosomoides polygyrus barkeri modify intestinal stem cells into a “revival” state, which is associated with a loss of helminth-expelling secretory cell types from the epithelium.
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spelling pubmed-93751592023-02-16 Helminths revive to survive Grainger, John R. Daw, Rufus H. J Exp Med Insights Helminth parasites are well known to have co-evolved a diverse arsenal of immunomodulatory factors to aid their persistence following infection. In this issue, Karo-Atar et al. (2022. J. Exp. Med. https://doi.org/10.1084/jem.20212311) demonstrate that products released by the gut-dwelling helminth Heligmosomoides polygyrus barkeri modify intestinal stem cells into a “revival” state, which is associated with a loss of helminth-expelling secretory cell types from the epithelium. Rockefeller University Press 2022-08-16 /pmc/articles/PMC9375159/ /pubmed/37559179 http://dx.doi.org/10.1084/jem.20221183 Text en © 2022 Grainger and Daw https://creativecommons.org/licenses/by-nc-sa/4.0/http://www.rupress.org/terms/This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms/). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 4.0 International license, as described at https://creativecommons.org/licenses/by-nc-sa/4.0/).
spellingShingle Insights
Grainger, John R.
Daw, Rufus H.
Helminths revive to survive
title Helminths revive to survive
title_full Helminths revive to survive
title_fullStr Helminths revive to survive
title_full_unstemmed Helminths revive to survive
title_short Helminths revive to survive
title_sort helminths revive to survive
topic Insights
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375159/
https://www.ncbi.nlm.nih.gov/pubmed/37559179
http://dx.doi.org/10.1084/jem.20221183
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