Immunotherapy for type 1 diabetes mellitus by adjuvant-free Schistosoma japonicum-egg tip-loaded asymmetric microneedle patch (STAMP)

BACKGROUND: Type 1 diabetes mellitus (T1DM) is an autoimmune disease mediated by autoreactive T cells and dominated by Th1 response polarization. Insulin replacement therapy faces great challenges to this autoimmune disease, requiring highly frequent daily administration. Intriguingly, the progressi...

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Detalles Bibliográficos
Autores principales: Huang, Haoming, Hu, Dian, Chen, Zhuo, Xu, Jiarong, Xu, Rengui, Gong, Yusheng, Fang, Zhengming, Wang, Ting, Chen, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375265/
https://www.ncbi.nlm.nih.gov/pubmed/35964125
http://dx.doi.org/10.1186/s12951-022-01581-9

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