Mesenchymal stromal cells pretreated with proinflammatory cytokines enhance skin wound healing via IL-6-dependent M2 polarization

BACKGROUND: Numerous studies have shown that mesenchymal stromal cells (MSCs) promote cutaneous wound healing via paracrine signaling. Our previous study found that the secretome of MSCs was significantly amplified by treatment with IFN-γ and TNF-α (IT). It has been known that macrophages are involv...

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Detalles Bibliográficos
Autores principales: Liu, Chenyang, Xu, Yan, Lu, Yichi, Du, Pan, Li, Xiaoxiao, Wang, Chengchun, Guo, Peng, Diao, Ling, Lu, Guozhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375394/
https://www.ncbi.nlm.nih.gov/pubmed/35964139
http://dx.doi.org/10.1186/s13287-022-02934-9

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