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Biological activity reduction and mitochondrial and lysosomal dysfunction of mesenchymal stem cells aging in vitro

BACKGROUND: Mesenchymal stem cells (MSCs) have been extensively used for the treatment of various diseases in preclinical and clinical trials. In vitro propagation is needed to attain enough cells for clinical use. However, cell aging and viability reduction caused by long-time culture have not been...

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Detalles Bibliográficos
Autores principales:	Zhang, Ge, Wang, Yuli, Lin, Jianhua, Wang, Bo, Mohsin, Ali, Cheng, Zhimin, Hao, Weijie, Gao, Wei-Qiang, Xu, Huiming, Guo, Meijin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375398/ https://www.ncbi.nlm.nih.gov/pubmed/35964126 http://dx.doi.org/10.1186/s13287-022-03107-4

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