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Single-cell transcriptomics reveals the cell fate transitions of human dopaminergic progenitors derived from hESCs

BACKGROUND: Midbrain dopaminergic (DA) progenitors derived from human pluripotent stem cells are considered to be a promising treatment for Parkinson’s disease (PD). However, the differentiation process produces undesired cell types, which influence the in vivo evaluation of DA cells. In this paper,...

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Detalles Bibliográficos
Autores principales: Liang, Lingmin, Tian, Yao, Feng, Lin, Wang, Chaoqun, Feng, Guihai, Stacey, Glyn Nigel, Shyh-Chang, Ng, Wu, Jun, Hu, Baoyang, Li, Wei, Hao, Jie, Wang, Liu, Wang, Yukai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375405/
https://www.ncbi.nlm.nih.gov/pubmed/35964138
http://dx.doi.org/10.1186/s13287-022-03104-7