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Insufficient S-adenosylhomocysteine hydrolase compromises the beneficial effect of diabetic BMSCs on diabetic cardiomyopathy

BACKGROUND: Autologous stem cell therapy is a promising strategy for cardiovascular diseases including diabetic cardiomyopathy (DCM), but conclusions from clinical trials were compromised. We assumed that diabetes might induce the dysfunction of stem cells and thus limit its therapeutic effect. This...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Zhang, Yuying, Chen, Kegong, Liu, Jie, Wu, Donghong, Cheng, Yao, Wang, Hongjie, Li, Yanbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375418/
https://www.ncbi.nlm.nih.gov/pubmed/35964109
http://dx.doi.org/10.1186/s13287-022-03099-1