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CTNNB1 mutations, TERT polymorphism and CD8+ cell densities in resected hepatocellular carcinoma are associated with longer time to recurrence

BACKGROUND: Hepatocellular carcinoma (HCC) is a fatal disease characterized by early genetic alterations in telomerase reverse transcriptase promoter (TERTp) and β-catenin (CTNNB1) genes and immune cell activation in the tumor microenvironment. As a novel approach, we wanted to assess patient surviv...

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Detalles Bibliográficos
Autores principales:	Ambrozkiewicz, Filip, Trailin, Andriy, Červenková, Lenka, Vaclavikova, Radka, Hanicinec, Vojtech, Allah, Mohammad Al Obeed, Palek, Richard, Třeška, Vladislav, Daum, Ondrej, Tonar, Zbyněk, Liška, Václav, Hemminki, Kari
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375422/ https://www.ncbi.nlm.nih.gov/pubmed/35962322 http://dx.doi.org/10.1186/s12885-022-09989-0

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