Cargando…

Circular RNA BIRC6 depletion promotes osteogenic differentiation of periodontal ligament stem cells via the miR-543/PTEN/PI3K/AKT/mTOR signaling pathway in the inflammatory microenvironment

BACKGROUND: Periodontal ligament stem cells (PDLSCs) are the ideal seed cells for periodontal tissue regeneration. It is well established that persistent inflammation significantly impairs the osteogenic differentiation capability of PDLSCs. Therefore, maintaining PDLSC osteogenic potential under th...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhao, Xinyuan, Sun, Wenjuan, Guo, Bing, Cui, Li
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375426/
https://www.ncbi.nlm.nih.gov/pubmed/35964136
http://dx.doi.org/10.1186/s13287-022-03093-7