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Evaluation of Prevalence of Side-Effects Associated with Booster Dose of mRNA-Based COVID-19 Vaccine Among Healthcare Workers in Eastern Province, Saudi Arabia: A Descriptive Cross-Sectional Study
BACKGROUND: The purpose of this study was to examine the mild and moderate side‐effects experienced by the healthcare workers (HCWs) in the Eastern Province of Saudi Arabia after receiving the booster dose of the Pfizer-BioNTech/BNT162b2 COVID‐19 vaccine. METHODS: We directed a descriptive cross-sec...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Dove
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375576/ https://www.ncbi.nlm.nih.gov/pubmed/35971558 http://dx.doi.org/10.2147/IDR.S374265 |
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author | Ali, Mohammad Daud Almadan, Leena Zakariya Alghamdi, Ruba Ahmed Alghamdi, Alanood Saleh Almarhoon, Sarah Ali Hassan, Yousif A M Ahmad, Ayaz Ghosn, Sherihan Ahmad Banu, Nuzhat Eltrafi, Zainab |
author_facet | Ali, Mohammad Daud Almadan, Leena Zakariya Alghamdi, Ruba Ahmed Alghamdi, Alanood Saleh Almarhoon, Sarah Ali Hassan, Yousif A M Ahmad, Ayaz Ghosn, Sherihan Ahmad Banu, Nuzhat Eltrafi, Zainab |
author_sort | Ali, Mohammad Daud |
collection | PubMed |
description | BACKGROUND: The purpose of this study was to examine the mild and moderate side‐effects experienced by the healthcare workers (HCWs) in the Eastern Province of Saudi Arabia after receiving the booster dose of the Pfizer-BioNTech/BNT162b2 COVID‐19 vaccine. METHODS: We directed a descriptive cross-sectional study among adults living in the Eastern Province of Saudi Arabia. A survey link was distributed through WhatsApp, SMS, or e-mail to HCWs. Participants’ general and demographic information were also collected, as well as information about any local and systemic side‐effects reported following vaccination. RESULTS: The results of this study showed that 81.84% (401/490) of the HCWs who contributed to this study reported the minimum COVID‐19 post‐vaccination side‐effect. Body pain (89%) and pain at the site of injection (88.73%) were the most frequent frequently reported side‐effects, followed by headache (28.68%), joint or bone pain (27.18%), muscle pain (26.43%), nausea or vomiting (21.2%), fever (18.95%), skin rashes (10.22%). History of chronic diseases had a 0.44‐fold increased risk of side-effects compared to no history of chronic diseases HCWs (adjusted odds ratio (aOR) = 0.44; 95% CI = 0.224, 0.880), and significant association of occupation with side-effects was also 1.61-fold increased risk compared to nonmedical ((aOR) = 1.61; 95% CI = 1.037, 2.513). CONCLUSION: According to this study, the Pfizer-BioNTech/BNT162b2 COVID-19 vaccine was safe when given to Saudi Arabian HCWs. All reported side‐effects were mild to moderate. The outcomes indicated that most participants had body pain and pain at the site of injection and fatigue is among the least reported side-effect post-booster dose. Healthcare was highly connected with more reporting of side‐effects. |
format | Online Article Text |
id | pubmed-9375576 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Dove |
record_format | MEDLINE/PubMed |
spelling | pubmed-93755762022-08-14 Evaluation of Prevalence of Side-Effects Associated with Booster Dose of mRNA-Based COVID-19 Vaccine Among Healthcare Workers in Eastern Province, Saudi Arabia: A Descriptive Cross-Sectional Study Ali, Mohammad Daud Almadan, Leena Zakariya Alghamdi, Ruba Ahmed Alghamdi, Alanood Saleh Almarhoon, Sarah Ali Hassan, Yousif A M Ahmad, Ayaz Ghosn, Sherihan Ahmad Banu, Nuzhat Eltrafi, Zainab Infect Drug Resist Original Research BACKGROUND: The purpose of this study was to examine the mild and moderate side‐effects experienced by the healthcare workers (HCWs) in the Eastern Province of Saudi Arabia after receiving the booster dose of the Pfizer-BioNTech/BNT162b2 COVID‐19 vaccine. METHODS: We directed a descriptive cross-sectional study among adults living in the Eastern Province of Saudi Arabia. A survey link was distributed through WhatsApp, SMS, or e-mail to HCWs. Participants’ general and demographic information were also collected, as well as information about any local and systemic side‐effects reported following vaccination. RESULTS: The results of this study showed that 81.84% (401/490) of the HCWs who contributed to this study reported the minimum COVID‐19 post‐vaccination side‐effect. Body pain (89%) and pain at the site of injection (88.73%) were the most frequent frequently reported side‐effects, followed by headache (28.68%), joint or bone pain (27.18%), muscle pain (26.43%), nausea or vomiting (21.2%), fever (18.95%), skin rashes (10.22%). History of chronic diseases had a 0.44‐fold increased risk of side-effects compared to no history of chronic diseases HCWs (adjusted odds ratio (aOR) = 0.44; 95% CI = 0.224, 0.880), and significant association of occupation with side-effects was also 1.61-fold increased risk compared to nonmedical ((aOR) = 1.61; 95% CI = 1.037, 2.513). CONCLUSION: According to this study, the Pfizer-BioNTech/BNT162b2 COVID-19 vaccine was safe when given to Saudi Arabian HCWs. All reported side‐effects were mild to moderate. The outcomes indicated that most participants had body pain and pain at the site of injection and fatigue is among the least reported side-effect post-booster dose. Healthcare was highly connected with more reporting of side‐effects. Dove 2022-08-09 /pmc/articles/PMC9375576/ /pubmed/35971558 http://dx.doi.org/10.2147/IDR.S374265 Text en © 2022 Ali et al. https://creativecommons.org/licenses/by-nc/3.0/This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/ (https://creativecommons.org/licenses/by-nc/3.0/) ). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php). |
spellingShingle | Original Research Ali, Mohammad Daud Almadan, Leena Zakariya Alghamdi, Ruba Ahmed Alghamdi, Alanood Saleh Almarhoon, Sarah Ali Hassan, Yousif A M Ahmad, Ayaz Ghosn, Sherihan Ahmad Banu, Nuzhat Eltrafi, Zainab Evaluation of Prevalence of Side-Effects Associated with Booster Dose of mRNA-Based COVID-19 Vaccine Among Healthcare Workers in Eastern Province, Saudi Arabia: A Descriptive Cross-Sectional Study |
title | Evaluation of Prevalence of Side-Effects Associated with Booster Dose of mRNA-Based COVID-19 Vaccine Among Healthcare Workers in Eastern Province, Saudi Arabia: A Descriptive Cross-Sectional Study |
title_full | Evaluation of Prevalence of Side-Effects Associated with Booster Dose of mRNA-Based COVID-19 Vaccine Among Healthcare Workers in Eastern Province, Saudi Arabia: A Descriptive Cross-Sectional Study |
title_fullStr | Evaluation of Prevalence of Side-Effects Associated with Booster Dose of mRNA-Based COVID-19 Vaccine Among Healthcare Workers in Eastern Province, Saudi Arabia: A Descriptive Cross-Sectional Study |
title_full_unstemmed | Evaluation of Prevalence of Side-Effects Associated with Booster Dose of mRNA-Based COVID-19 Vaccine Among Healthcare Workers in Eastern Province, Saudi Arabia: A Descriptive Cross-Sectional Study |
title_short | Evaluation of Prevalence of Side-Effects Associated with Booster Dose of mRNA-Based COVID-19 Vaccine Among Healthcare Workers in Eastern Province, Saudi Arabia: A Descriptive Cross-Sectional Study |
title_sort | evaluation of prevalence of side-effects associated with booster dose of mrna-based covid-19 vaccine among healthcare workers in eastern province, saudi arabia: a descriptive cross-sectional study |
topic | Original Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375576/ https://www.ncbi.nlm.nih.gov/pubmed/35971558 http://dx.doi.org/10.2147/IDR.S374265 |
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