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Diabetes Mellitus is Associated With Higher COVID-19 Mortality Rates in Sub-Saharan Africa: A Systematic Review and Meta-analysis
The rate of COVID-19-related mortality among patients with diabetes mellitus in Sub-Saharan Africa (SSA) is unknown. The current study aimed to determine the mortality rate of COVID-19 among diabetes patients in SSA. We performed a systematic review of research articles until July 1, 2021. A literat...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375835/ https://www.ncbi.nlm.nih.gov/pubmed/35978734 http://dx.doi.org/10.7759/cureus.26877 |
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author | Bepouka, Ben Odio, Ossam Mangala, Donat Mayasi, Nadine Mandina, Madone Longokolo, Murielle Makulo, Jean Robert Mbula, Marcel Kayembe, Jean Marie Situakibanza, Hippolyte |
author_facet | Bepouka, Ben Odio, Ossam Mangala, Donat Mayasi, Nadine Mandina, Madone Longokolo, Murielle Makulo, Jean Robert Mbula, Marcel Kayembe, Jean Marie Situakibanza, Hippolyte |
author_sort | Bepouka, Ben |
collection | PubMed |
description | The rate of COVID-19-related mortality among patients with diabetes mellitus in Sub-Saharan Africa (SSA) is unknown. The current study aimed to determine the mortality rate of COVID-19 among diabetes patients in SSA. We performed a systematic review of research articles until July 1, 2021. A literature review was conducted in accordance with the PRISMA guidelines to gather relevant data. A random effects model was used to calculate odds ratios and 95% confidence intervals (CIs). We used Egger's tests and Begg's funnel plot to examine publication bias. The mortality rate of 7778 COVID-19 patients was analyzed using data from seven studies. The I(2) test was used to determine the heterogeneity between studies. The meta-analysis revealed that diabetes mellitus was linked to a 1.39-fold increase in the risk of death among COVID-19 inpatients (95% CI: 1.02-1.76). According to our findings, there was no significant heterogeneity between studies, and there was no publication bias. The present review describes an association between diabetes mellitus and the risk of COVID-19 mortality in SSA. |
format | Online Article Text |
id | pubmed-9375835 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-93758352022-08-16 Diabetes Mellitus is Associated With Higher COVID-19 Mortality Rates in Sub-Saharan Africa: A Systematic Review and Meta-analysis Bepouka, Ben Odio, Ossam Mangala, Donat Mayasi, Nadine Mandina, Madone Longokolo, Murielle Makulo, Jean Robert Mbula, Marcel Kayembe, Jean Marie Situakibanza, Hippolyte Cureus Endocrinology/Diabetes/Metabolism The rate of COVID-19-related mortality among patients with diabetes mellitus in Sub-Saharan Africa (SSA) is unknown. The current study aimed to determine the mortality rate of COVID-19 among diabetes patients in SSA. We performed a systematic review of research articles until July 1, 2021. A literature review was conducted in accordance with the PRISMA guidelines to gather relevant data. A random effects model was used to calculate odds ratios and 95% confidence intervals (CIs). We used Egger's tests and Begg's funnel plot to examine publication bias. The mortality rate of 7778 COVID-19 patients was analyzed using data from seven studies. The I(2) test was used to determine the heterogeneity between studies. The meta-analysis revealed that diabetes mellitus was linked to a 1.39-fold increase in the risk of death among COVID-19 inpatients (95% CI: 1.02-1.76). According to our findings, there was no significant heterogeneity between studies, and there was no publication bias. The present review describes an association between diabetes mellitus and the risk of COVID-19 mortality in SSA. Cureus 2022-07-15 /pmc/articles/PMC9375835/ /pubmed/35978734 http://dx.doi.org/10.7759/cureus.26877 Text en Copyright © 2022, Bepouka et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Endocrinology/Diabetes/Metabolism Bepouka, Ben Odio, Ossam Mangala, Donat Mayasi, Nadine Mandina, Madone Longokolo, Murielle Makulo, Jean Robert Mbula, Marcel Kayembe, Jean Marie Situakibanza, Hippolyte Diabetes Mellitus is Associated With Higher COVID-19 Mortality Rates in Sub-Saharan Africa: A Systematic Review and Meta-analysis |
title | Diabetes Mellitus is Associated With Higher COVID-19 Mortality Rates in Sub-Saharan Africa: A Systematic Review and Meta-analysis |
title_full | Diabetes Mellitus is Associated With Higher COVID-19 Mortality Rates in Sub-Saharan Africa: A Systematic Review and Meta-analysis |
title_fullStr | Diabetes Mellitus is Associated With Higher COVID-19 Mortality Rates in Sub-Saharan Africa: A Systematic Review and Meta-analysis |
title_full_unstemmed | Diabetes Mellitus is Associated With Higher COVID-19 Mortality Rates in Sub-Saharan Africa: A Systematic Review and Meta-analysis |
title_short | Diabetes Mellitus is Associated With Higher COVID-19 Mortality Rates in Sub-Saharan Africa: A Systematic Review and Meta-analysis |
title_sort | diabetes mellitus is associated with higher covid-19 mortality rates in sub-saharan africa: a systematic review and meta-analysis |
topic | Endocrinology/Diabetes/Metabolism |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375835/ https://www.ncbi.nlm.nih.gov/pubmed/35978734 http://dx.doi.org/10.7759/cureus.26877 |
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