Hand-Foot Syndrome Presentation Post-Capecitabine Treatment in a Black Patient

Palmar-plantar erythrodysesthesia, commonly known as hand-foot syndrome (HFS), is a side-effect of cancer chemotherapeutic agents such as capecitabine. Patients with HFS oftentimes present with palmoplantar numbness, tingling, burning pain, and/or hyperpigmentation; in advanced grades, blistering an...

Descripción completa

Detalles Bibliográficos
Autores principales: Whorton, Allison E, Razzak, Abrahim N, Jha, Pinky
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2022
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375837/
https://www.ncbi.nlm.nih.gov/pubmed/35978746
http://dx.doi.org/10.7759/cureus.26891
_version_ 1784768041269067776
author Whorton, Allison E
Razzak, Abrahim N
Jha, Pinky
author_facet Whorton, Allison E
Razzak, Abrahim N
Jha, Pinky
author_sort Whorton, Allison E
collection PubMed
description Palmar-plantar erythrodysesthesia, commonly known as hand-foot syndrome (HFS), is a side-effect of cancer chemotherapeutic agents such as capecitabine. Patients with HFS oftentimes present with palmoplantar numbness, tingling, burning pain, and/or hyperpigmentation; in advanced grades, blistering and ulceration may occur. In this article, we present the case of a Black patient with grade 1 HFS post-capecitabine treatment for metastasized breast cancer. Prompt recognition for atypical HFS symptom presentation in people of color and discontinuation of capecitabine with supportive treatment can prevent progression to grade 2+ HFS that limits activities of daily living (ADLs).
format Online
Article
Text
id pubmed-9375837
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Cureus
record_format MEDLINE/PubMed
spelling pubmed-93758372022-08-16 Hand-Foot Syndrome Presentation Post-Capecitabine Treatment in a Black Patient Whorton, Allison E Razzak, Abrahim N Jha, Pinky Cureus Internal Medicine Palmar-plantar erythrodysesthesia, commonly known as hand-foot syndrome (HFS), is a side-effect of cancer chemotherapeutic agents such as capecitabine. Patients with HFS oftentimes present with palmoplantar numbness, tingling, burning pain, and/or hyperpigmentation; in advanced grades, blistering and ulceration may occur. In this article, we present the case of a Black patient with grade 1 HFS post-capecitabine treatment for metastasized breast cancer. Prompt recognition for atypical HFS symptom presentation in people of color and discontinuation of capecitabine with supportive treatment can prevent progression to grade 2+ HFS that limits activities of daily living (ADLs). Cureus 2022-07-15 /pmc/articles/PMC9375837/ /pubmed/35978746 http://dx.doi.org/10.7759/cureus.26891 Text en Copyright © 2022, Whorton et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Whorton, Allison E
Razzak, Abrahim N
Jha, Pinky
Hand-Foot Syndrome Presentation Post-Capecitabine Treatment in a Black Patient
title Hand-Foot Syndrome Presentation Post-Capecitabine Treatment in a Black Patient
title_full Hand-Foot Syndrome Presentation Post-Capecitabine Treatment in a Black Patient
title_fullStr Hand-Foot Syndrome Presentation Post-Capecitabine Treatment in a Black Patient
title_full_unstemmed Hand-Foot Syndrome Presentation Post-Capecitabine Treatment in a Black Patient
title_short Hand-Foot Syndrome Presentation Post-Capecitabine Treatment in a Black Patient
title_sort hand-foot syndrome presentation post-capecitabine treatment in a black patient
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375837/
https://www.ncbi.nlm.nih.gov/pubmed/35978746
http://dx.doi.org/10.7759/cureus.26891
work_keys_str_mv AT whortonallisone handfootsyndromepresentationpostcapecitabinetreatmentinablackpatient
AT razzakabrahimn handfootsyndromepresentationpostcapecitabinetreatmentinablackpatient
AT jhapinky handfootsyndromepresentationpostcapecitabinetreatmentinablackpatient

Ejemplares similares