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Functional and structural characteristics of HLA-B*13:01-mediated specific T cells reaction in dapsone-induced drug hypersensitivity

BACKGROUND: Severe cutaneous adverse drug reactions (SCARs) are a group of serious clinical conditions caused by immune reaction to certain drugs. The allelic variance of human leukocyte antigens of HLA-B*13:01 has been strongly associated with hypersensitivities induced by dapsone (DDS). T-cell rec...

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Detalles Bibliográficos
Autores principales:	Jiang, Haiqin, Wang, Chuang-Wei, Wang, Zhaoxi, Dai, Yufei, Zhu, Yanping, Lee, Yun-Shien, Cao, Yang, Chung, Wen-Hung, Ouyang, Songying, Wang, Hongsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9375929/ https://www.ncbi.nlm.nih.gov/pubmed/35964029 http://dx.doi.org/10.1186/s12929-022-00845-8

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