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Functional antagonism between CagA and DLC1 in gastric cancer

Helicobacter (H.) pylori-induced gastritis is a risk factor for gastric cancer (GC). Deleted-in-liver-cancer-1 (DLC1/ARHGAP7) inhibits RHOA, a downstream mediator of virulence factor cytotoxin-A (CagA) signalling and driver of consensus-molecular-subtype-2 diffuse GC. DLC1 located to enterochromaffi...

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Detalles Bibliográficos
Autores principales:	Hinsenkamp, Isabel, Köhler, Jan P., Flächsenhaar, Christoph, Hitkova, Ivana, Meessen, Sabine Eberhart, Gaiser, Timo, Wieland, Thomas, Weiss, Christel, Röcken, Christoph, Mowat, Michael, Quante, Michael, Taxauer, Karin, Mejias-Luque, Raquel, Gerhard, Markus, Vogelmann, Roger, Meindl-Beinker, Nadja, Ebert, Matthias, Burgermeister, Elke
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376073/ https://www.ncbi.nlm.nih.gov/pubmed/35963849 http://dx.doi.org/10.1038/s41420-022-01134-x

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