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A high-throughput microfluidic device based on controlled incremental filtration to enable centrifugation-free, low extracorporeal volume leukapheresis
Leukapheresis, the extracorporeal separation of white blood cells (WBCs) from red blood cells (RBCs) and platelets (PLTs), is a life-saving procedure used for treating patients with cancer and other conditions, and as the initial step in the manufacturing of cellular and gene-based therapies. Well-t...
Autores principales: | Lezzar, Dalia L., Lam, Fong W., Huerta, Ravin, Mukhamedshin, Anton, Lu, Madeleine, Shevkoplyas, Sergey S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376077/ https://www.ncbi.nlm.nih.gov/pubmed/35963876 http://dx.doi.org/10.1038/s41598-022-16748-5 |
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