Cargando…

Identification of small molecules targeting homoserine acetyl transferase from Mycobacterium tuberculosis and Staphylococcus aureus

There is an urgent need to validate new drug targets and identify small molecules that possess activity against both drug-resistant and drug-sensitive bacteria. The enzymes belonging to amino acid biosynthesis have been shown to be essential for growth in vitro, in vivo and have not been exploited m...

Descripción completa

Detalles Bibliográficos
Autores principales: Chaudhary, Deepika, Singh, Avantika, Marzuki, Mardiana, Ghosh, Abhirupa, Kidwai, Saqib, Gosain, Tannu Priya, Chawla, Kiran, Gupta, Sonu Kumar, Agarwal, Nisheeth, Saha, Sudipto, Kumar, Yashwant, Thakur, Krishan Gopal, Singhal, Amit, Singh, Ramandeep
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376091/
https://www.ncbi.nlm.nih.gov/pubmed/35963878
http://dx.doi.org/10.1038/s41598-022-16468-w