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Diverse synthesis of α-tertiary amines and tertiary alcohols via desymmetric reduction of malonic esters
Amines and alcohols with a fully substituted α-carbon are structures of great value in organic synthesis and drug discovery. While conventional methods towards these motifs often rely on enantioselective carbon-carbon or carbon-heteroatom bond formation reactions, a desymmetric method is developed h...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376102/ https://www.ncbi.nlm.nih.gov/pubmed/35963867 http://dx.doi.org/10.1038/s41467-022-32560-1 |