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Development of actionable targets of multi-kinase inhibitors (AToMI) screening platform to dissect kinase targets of staurosporines in glioblastoma cells

Therapeutic resistance to kinase inhibitors constitutes a major unresolved clinical challenge in cancer and especially in glioblastoma. Multi-kinase inhibitors may be used for simultaneous targeting of multiple target kinases and thereby potentially overcome kinase inhibitor resistance. However, in...

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Detalles Bibliográficos
Autores principales: Denisova, Oxana V., Merisaari, Joni, Kaur, Amanpreet, Yetukuri, Laxman, Jumppanen, Mikael, von Schantz-Fant, Carina, Ohlmeyer, Michael, Wennerberg, Krister, Aittokallio, Tero, Taipale, Mikko, Westermarck, Jukka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376105/
https://www.ncbi.nlm.nih.gov/pubmed/35963891
http://dx.doi.org/10.1038/s41598-022-18118-7

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