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Development of actionable targets of multi-kinase inhibitors (AToMI) screening platform to dissect kinase targets of staurosporines in glioblastoma cells
Therapeutic resistance to kinase inhibitors constitutes a major unresolved clinical challenge in cancer and especially in glioblastoma. Multi-kinase inhibitors may be used for simultaneous targeting of multiple target kinases and thereby potentially overcome kinase inhibitor resistance. However, in...
Autores principales: | Denisova, Oxana V., Merisaari, Joni, Kaur, Amanpreet, Yetukuri, Laxman, Jumppanen, Mikael, von Schantz-Fant, Carina, Ohlmeyer, Michael, Wennerberg, Krister, Aittokallio, Tero, Taipale, Mikko, Westermarck, Jukka |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376105/ https://www.ncbi.nlm.nih.gov/pubmed/35963891 http://dx.doi.org/10.1038/s41598-022-18118-7 |
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