Primary hypothyroidism resolves after switching from L‐thyroxine solid tablets to liquid oral substitution. A rare case without evidence of an underlying gastrointestinal malabsorption syndrome

A case of refractory primary hypothyroidism is presented. Despite laboratory‐guided hormonal substitution, the patient remained hypothyroid. Multiple diagnostic tests ruled out all known causes of levothyroxine malabsorption. Interestingly, clinical and laboratory responding was promptly achieved, a...

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Autores principales: Stupperich, Sophie, Kotliarevskaia, Jessica, Nies, Reinhold, Paparoupa, Maria, Wittig, Andreas, Schuppert, Frank
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376134/
https://www.ncbi.nlm.nih.gov/pubmed/35990384
http://dx.doi.org/10.1002/ccr3.6223
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author Stupperich, Sophie
Kotliarevskaia, Jessica
Nies, Reinhold
Paparoupa, Maria
Wittig, Andreas
Schuppert, Frank
author_facet Stupperich, Sophie
Kotliarevskaia, Jessica
Nies, Reinhold
Paparoupa, Maria
Wittig, Andreas
Schuppert, Frank
author_sort Stupperich, Sophie
collection PubMed
description A case of refractory primary hypothyroidism is presented. Despite laboratory‐guided hormonal substitution, the patient remained hypothyroid. Multiple diagnostic tests ruled out all known causes of levothyroxine malabsorption. Interestingly, clinical and laboratory responding was promptly achieved, after switching the application format from solid tablets to liquid formula.
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spelling pubmed-93761342022-08-18 Primary hypothyroidism resolves after switching from L‐thyroxine solid tablets to liquid oral substitution. A rare case without evidence of an underlying gastrointestinal malabsorption syndrome Stupperich, Sophie Kotliarevskaia, Jessica Nies, Reinhold Paparoupa, Maria Wittig, Andreas Schuppert, Frank Clin Case Rep Case Report A case of refractory primary hypothyroidism is presented. Despite laboratory‐guided hormonal substitution, the patient remained hypothyroid. Multiple diagnostic tests ruled out all known causes of levothyroxine malabsorption. Interestingly, clinical and laboratory responding was promptly achieved, after switching the application format from solid tablets to liquid formula. John Wiley and Sons Inc. 2022-08-14 /pmc/articles/PMC9376134/ /pubmed/35990384 http://dx.doi.org/10.1002/ccr3.6223 Text en © 2022 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Report
Stupperich, Sophie
Kotliarevskaia, Jessica
Nies, Reinhold
Paparoupa, Maria
Wittig, Andreas
Schuppert, Frank
Primary hypothyroidism resolves after switching from L‐thyroxine solid tablets to liquid oral substitution. A rare case without evidence of an underlying gastrointestinal malabsorption syndrome
title Primary hypothyroidism resolves after switching from L‐thyroxine solid tablets to liquid oral substitution. A rare case without evidence of an underlying gastrointestinal malabsorption syndrome
title_full Primary hypothyroidism resolves after switching from L‐thyroxine solid tablets to liquid oral substitution. A rare case without evidence of an underlying gastrointestinal malabsorption syndrome
title_fullStr Primary hypothyroidism resolves after switching from L‐thyroxine solid tablets to liquid oral substitution. A rare case without evidence of an underlying gastrointestinal malabsorption syndrome
title_full_unstemmed Primary hypothyroidism resolves after switching from L‐thyroxine solid tablets to liquid oral substitution. A rare case without evidence of an underlying gastrointestinal malabsorption syndrome
title_short Primary hypothyroidism resolves after switching from L‐thyroxine solid tablets to liquid oral substitution. A rare case without evidence of an underlying gastrointestinal malabsorption syndrome
title_sort primary hypothyroidism resolves after switching from l‐thyroxine solid tablets to liquid oral substitution. a rare case without evidence of an underlying gastrointestinal malabsorption syndrome
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376134/
https://www.ncbi.nlm.nih.gov/pubmed/35990384
http://dx.doi.org/10.1002/ccr3.6223
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