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Advance trends in targeting homology-directed repair for accurate gene editing: An inclusive review of small molecules and modified CRISPR-Cas9 systems

[Image: see text] Introduction: Clustered regularly interspaced short palindromic repeat and its associated protein (CRISPR-Cas)-based technologies generate targeted modifications in host genome by inducing site-specific double-strand breaks (DSBs) that can serve as a substrate for homology-directed...

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Detalles Bibliográficos
Autores principales: Shams, Forough, Bayat, Hadi, Mohammadian, Omid, Mahboudi, Somayeh, Vahidnezhad, Hassan, Soosanabadi, Mohsen, Rahimpour, Azam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Tabriz University of Medical Sciences (TUOMS Publishing Group) 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376165/
https://www.ncbi.nlm.nih.gov/pubmed/35975201
http://dx.doi.org/10.34172/bi.2022.23871