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Advance trends in targeting homology-directed repair for accurate gene editing: An inclusive review of small molecules and modified CRISPR-Cas9 systems
[Image: see text] Introduction: Clustered regularly interspaced short palindromic repeat and its associated protein (CRISPR-Cas)-based technologies generate targeted modifications in host genome by inducing site-specific double-strand breaks (DSBs) that can serve as a substrate for homology-directed...
Autores principales: | Shams, Forough, Bayat, Hadi, Mohammadian, Omid, Mahboudi, Somayeh, Vahidnezhad, Hassan, Soosanabadi, Mohsen, Rahimpour, Azam |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Tabriz University of Medical Sciences (TUOMS Publishing Group)
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376165/ https://www.ncbi.nlm.nih.gov/pubmed/35975201 http://dx.doi.org/10.34172/bi.2022.23871 |
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