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Radiation‐induced pseudomembranous tracheobronchitis: A report of two cases

Radiation therapy can cause radiation pneumonitis, organizing pneumonia, and lung fibrosis. Radiation‐induced pseudomembranous bronchitis is a rare condition. Here, we describe a rare case each of pseudomembranous tracheobronchitis and pseudomembrane with total bronchial obstruction which developed...

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Autor principal: Choi, Hye Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Australia, Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376171/
https://www.ncbi.nlm.nih.gov/pubmed/35793785
http://dx.doi.org/10.1111/1759-7714.14561
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author Choi, Hye Sook
author_facet Choi, Hye Sook
author_sort Choi, Hye Sook
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description Radiation therapy can cause radiation pneumonitis, organizing pneumonia, and lung fibrosis. Radiation‐induced pseudomembranous bronchitis is a rare condition. Here, we describe a rare case each of pseudomembranous tracheobronchitis and pseudomembrane with total bronchial obstruction which developed after thoracic radiotherapy. A 50‐year‐old man presented paroxysmal severe cough 1 month after concurrent chemoradiotherapy for small‐cell lung cancer. Bronchoscopy revealed a whitish membrane in the trachea and bronchus, which were the fields of radiation. Another 60‐year‐old man complained of dyspnea 7 months after radiation therapy for metastatic lymph node adenocarcinoma. Bronchoscopy demonstrated a membrane with total obstruction of right lower lobar bronchus, which was the area of radiation. The pathological findings of histological examination in both cases demonstrated radiation‐induced pseudomembranous tracheobronchitis. Patients in both cases responded well to steroids and the pseudomembrane disappeared. If patients who have received thoracic radiation therapy complain of persistent cough, bronchoscopy may be helpful.
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spelling pubmed-93761712022-08-18 Radiation‐induced pseudomembranous tracheobronchitis: A report of two cases Choi, Hye Sook Thorac Cancer Case Reports Radiation therapy can cause radiation pneumonitis, organizing pneumonia, and lung fibrosis. Radiation‐induced pseudomembranous bronchitis is a rare condition. Here, we describe a rare case each of pseudomembranous tracheobronchitis and pseudomembrane with total bronchial obstruction which developed after thoracic radiotherapy. A 50‐year‐old man presented paroxysmal severe cough 1 month after concurrent chemoradiotherapy for small‐cell lung cancer. Bronchoscopy revealed a whitish membrane in the trachea and bronchus, which were the fields of radiation. Another 60‐year‐old man complained of dyspnea 7 months after radiation therapy for metastatic lymph node adenocarcinoma. Bronchoscopy demonstrated a membrane with total obstruction of right lower lobar bronchus, which was the area of radiation. The pathological findings of histological examination in both cases demonstrated radiation‐induced pseudomembranous tracheobronchitis. Patients in both cases responded well to steroids and the pseudomembrane disappeared. If patients who have received thoracic radiation therapy complain of persistent cough, bronchoscopy may be helpful. John Wiley & Sons Australia, Ltd 2022-07-06 2022-08 /pmc/articles/PMC9376171/ /pubmed/35793785 http://dx.doi.org/10.1111/1759-7714.14561 Text en © 2022 The Author. Thoracic Cancer published by China Lung Oncology Group and John Wiley & Sons Australia, Ltd. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Choi, Hye Sook
Radiation‐induced pseudomembranous tracheobronchitis: A report of two cases
title Radiation‐induced pseudomembranous tracheobronchitis: A report of two cases
title_full Radiation‐induced pseudomembranous tracheobronchitis: A report of two cases
title_fullStr Radiation‐induced pseudomembranous tracheobronchitis: A report of two cases
title_full_unstemmed Radiation‐induced pseudomembranous tracheobronchitis: A report of two cases
title_short Radiation‐induced pseudomembranous tracheobronchitis: A report of two cases
title_sort radiation‐induced pseudomembranous tracheobronchitis: a report of two cases
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376171/
https://www.ncbi.nlm.nih.gov/pubmed/35793785
http://dx.doi.org/10.1111/1759-7714.14561
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