Emerging role of non-coding RNAs in glucose metabolic reprogramming and chemoresistance in colorectal cancer

Metabolic reprogramming plays a critical role in colorectal cancer (CRC). It contributes to CRC by shaping metabolic phenotypes and causing uncontrolled proliferation of CRC cells. Glucose metabolic reprogramming is common in carcinogenesis and cancer progression. Growing evidence has implicated the...

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Autores principales: Yan, Shushan, Wang, Shufeng, Wang, Xinyi, Dai, Wenqing, Chu, Jinjin, Cheng, Min, Guo, Zhiliang, Xu, Donghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376248/
https://www.ncbi.nlm.nih.gov/pubmed/35978828
http://dx.doi.org/10.3389/fonc.2022.954329
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author Yan, Shushan
Wang, Shufeng
Wang, Xinyi
Dai, Wenqing
Chu, Jinjin
Cheng, Min
Guo, Zhiliang
Xu, Donghua
author_facet Yan, Shushan
Wang, Shufeng
Wang, Xinyi
Dai, Wenqing
Chu, Jinjin
Cheng, Min
Guo, Zhiliang
Xu, Donghua
author_sort Yan, Shushan
collection PubMed
description Metabolic reprogramming plays a critical role in colorectal cancer (CRC). It contributes to CRC by shaping metabolic phenotypes and causing uncontrolled proliferation of CRC cells. Glucose metabolic reprogramming is common in carcinogenesis and cancer progression. Growing evidence has implicated the modifying effects of non-coding RNAs (ncRNAs) in glucose metabolic reprogramming and chemoresistance in CRC. In this review, we have summarized currently published studies investigating the role of ncRNAs in glucose metabolic alterations and chemoresistance in CRC. Elucidating the interplay between ncRNAs and glucose metabolic reprogramming provides insight into exploring novel biomarkers for the diagnosis and prognosis prediction of CRC.
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spelling pubmed-93762482022-08-16 Emerging role of non-coding RNAs in glucose metabolic reprogramming and chemoresistance in colorectal cancer Yan, Shushan Wang, Shufeng Wang, Xinyi Dai, Wenqing Chu, Jinjin Cheng, Min Guo, Zhiliang Xu, Donghua Front Oncol Oncology Metabolic reprogramming plays a critical role in colorectal cancer (CRC). It contributes to CRC by shaping metabolic phenotypes and causing uncontrolled proliferation of CRC cells. Glucose metabolic reprogramming is common in carcinogenesis and cancer progression. Growing evidence has implicated the modifying effects of non-coding RNAs (ncRNAs) in glucose metabolic reprogramming and chemoresistance in CRC. In this review, we have summarized currently published studies investigating the role of ncRNAs in glucose metabolic alterations and chemoresistance in CRC. Elucidating the interplay between ncRNAs and glucose metabolic reprogramming provides insight into exploring novel biomarkers for the diagnosis and prognosis prediction of CRC. Frontiers Media S.A. 2022-08-01 /pmc/articles/PMC9376248/ /pubmed/35978828 http://dx.doi.org/10.3389/fonc.2022.954329 Text en Copyright © 2022 Yan, Wang, Wang, Dai, Chu, Cheng, Guo and Xu https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Yan, Shushan
Wang, Shufeng
Wang, Xinyi
Dai, Wenqing
Chu, Jinjin
Cheng, Min
Guo, Zhiliang
Xu, Donghua
Emerging role of non-coding RNAs in glucose metabolic reprogramming and chemoresistance in colorectal cancer
title Emerging role of non-coding RNAs in glucose metabolic reprogramming and chemoresistance in colorectal cancer
title_full Emerging role of non-coding RNAs in glucose metabolic reprogramming and chemoresistance in colorectal cancer
title_fullStr Emerging role of non-coding RNAs in glucose metabolic reprogramming and chemoresistance in colorectal cancer
title_full_unstemmed Emerging role of non-coding RNAs in glucose metabolic reprogramming and chemoresistance in colorectal cancer
title_short Emerging role of non-coding RNAs in glucose metabolic reprogramming and chemoresistance in colorectal cancer
title_sort emerging role of non-coding rnas in glucose metabolic reprogramming and chemoresistance in colorectal cancer
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9376248/
https://www.ncbi.nlm.nih.gov/pubmed/35978828
http://dx.doi.org/10.3389/fonc.2022.954329
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